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Vaxneuvance® (PNEU-C-15), Prevnar™20 (PNEU-C-20) and Capvaxive® (Pneu-C-21)

Pneumococcal Disease

Pneumococcal disease is caused by different strains of the bacteria Streptococcus pneumoniae (S. pneumoniae). It is spread through respiratory droplets from direct or indirect contact. Anyone can get a pneumococcal infection. Infections can lead to meningitis, serious blood infections (sepsis), pneumonia (lung infection), ear infections or sinus infections.

The disease can be serious in children under two years of age, people with certain medical conditions or other risk factors, and adults 65 years of age or older.  Vaccination is the best protection.

Vaccine Benefits

Pneumococcal vaccines are recommended for routine immunization of infants, children and adults, as well as those who are at higher risk of getting very sick from an infection. Pneumococcal vaccines (Vaxneuvance® (PNEU-C-15), Prevnar™20 (PNEU-C-20) and Capvaxive® (Pneu-C-21) are approved by Health Canada and are safe and effective. They are used not only in Canada, but around the world.

  • Prevnar™20 protects against 20 different strains of pneumococcal
  • Vaxneuvance® protects against 15 strains.
  • Capvaxive® protects against 21 strains including 10 strains that are not in the other vaccines.

The vaccines work by helping the body to make its own antibodies. The vaccines provide 70 to 95 per cent protection

Vaccine Side Effects and Risks

The vaccine is generally well tolerated. Vaccine side effects are usually mild and last one to two days. Common reactions include soreness, redness and/or swelling where the vaccine was given, fever, drowsiness, loss of appetite, headache, muscle or joint ache, chills and/or fussiness (irritability) – infants only.

In rare cases, serious reactions such as trouble breathing, hives, rash, swelling in the throat and face, a fast heartbeat, dizziness or weakness can occur. These reactions are usually temporary and can be treated. Please stay at the clinic for 15 minutes after vaccination so staff can monitor for any reactions.

People Who Should Get a Pneumococcal Vaccine

Pneumococcal vaccines are free (publicly funded) for the following groups.

Vaccine Eligibility
Vaxneuvance® (PNEU-C-15) Routine infant immunization at 2, 4, and 12 months of age.
Prevnar™20 (PNEU-C-20)
  • Infants and children 6 weeks to 4 years at higher risk who have not completed a PNEU-C-13 series.
  • Infants and children 6 weeks to 17 years at higher risk who have completed a PNEU-C-13 series*.
  • Individuals 6 weeks to 64 years with certain chronic health conditions.
  • Close contacts during outbreak situations, including homeless and underhoused individuals.
Capvaxive® (Pneu-C-21) Individuals 65 years of age and older who have not received a publicly funded pneumococcal vaccine.

* No additional doses are needed for children who have already received at least one dose of PNEU-C-20.

These vaccines can be given at the same time as other vaccines including influenza and COVID-19.

They are only given to individuals who have not previously had a pneumococcal vaccine series. Talk to your health care provider to determine your vaccine eligibility.

For Individuals Not Eligible for Public Funding

If you are not eligible for the free vaccine, speak to your health care provider to see if it is recommended for you. It may be available for private purchase or check with your private health coverage if it is covered for you.

People Who Should Not Get the Vaccine

  • Have had a severe reaction to a pneumococcal containing vaccine in the past.
  • Have an allergy to polysorbate.
  • People who are moderately or severely ill should usually wait until they recover. However, a mild fever or upper respiratory infection (for example having a cold) is not a reason to delay vaccination.
  • If you are pregnant or breastfeeding, think you may be pregnant or are planning to have a baby, talk to your health care provider before getting this vaccine.

More Information

  • Talk to your health care provider or Toronto Public Health at 416-338-7600.
  • Call 811 to connect to a registered nurse day or night for free, secure, and confidential health advice.
Date modified: August 18, 2026