Adverse Events Following Immunization (AEFI)
An AEFI is any event or reaction that occurs after receiving a vaccine. A causal relationship does not need to be proven before reporting. Of particular interest are those of a serious nature, requiring urgent medical attention or are unusual or unexpected events.
When to Report
Report an AEFI when:
- there is a concern to the patient, caregiver or health professional
- there is an unexpected reaction in terms of type or frequency
- there is a severe reaction requiring hospitalization or urgent medical attention
- it is within 30 days after administering a live vaccine (such as measles, mumps, rubella or chickenpox)
- is up to 8 weeks for immune-mediated events
How to Report
Call the Immunization Nurses’ Line at 416-338-2030 or fax the completed AEFI Reporting Form (Public Health Ontario) to 416-338-2028.
Note: If the form doesn’t open from the link above, download it using the download icon on the top right of the page. Use Adobe’s free Acrobat Reader software to complete and save the fillable form.
What to Report
|What to report|
|Patient||unique identifier, date of birth and sex|
|Immunization event(s)||province/territory where given, date, all vaccines given including name, manufacturer, lot number, administration site and route, as well as the number in series of vaccine doses if relevant|
|Adverse event(s)||description, including time of first onset following immunization, duration, health care utilization, treatment and outcome|
|Relevant medical history||underlying disease, known allergies, prior AEFI|
|Associated event(s)||acute illness, current medication, injury, exposure to environmental toxins|
Communicating with Parents
See the Ministry parent information sheet on vaccine safety, June 2016
How AEFI Reports are Tracked
To ensure the safety of vaccines, a surveillance system is set up to monitor adverse events and unusual occurrences. All adverse events investigated by Toronto Public Health are forwarded to the province, then to Public Health Agency of Canada. Adverse events are also compared internationally.
For More Information
- Call the Immunization Nursing Line at 416-338-2030
- Refer to the Provincial Case Definitions for Reportable Diseases, revised April 2015